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NIGHTTIME SEVERE COLD AND FLU 325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1 capsule by CVS HEALTH CORP
NIGHTTIME SEVERE COLD AND FLU, 325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1, capsule Drug class: Antihistamine; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist; alpha-1 Adrenergic Agonist. Available over the counter. Listed by CVS HEALTH CORP.
Over the counter

NIGHTTIME SEVERE COLD AND FLU

ACETAMINOPHEN, DEXTROMETHORPHAN HBR, DOXYLAMINE SUCCINATE, PHENYLEPHRINE HCL

Listed by CVS HEALTH CORP

Strength
325 mg/1, 10 mg/1, 6.25 mg/1, 5 mg/1
Form
Capsule
Route
Oral
Class
Antihistamine; Sigma-1 Agonist; Uncompetitive…

What it contains

  • Phenylephrine Hydrochloride 325 mg/1
  • Acetaminophen 10 mg/1
  • Dextromethorphan Hydrobromide 6.25 mg/1
  • Doxylamine Succinate 5 mg/1

This is a combination product. It is not interchangeable with a single-ingredient medicine containing only one of these.

FDA record

Dosage form Capsule
Route Oral
Drug class Antihistamine; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist; alpha-1 Adrenergic Agonist
Approval route OTC monograph
NDC code 51316-526
FDA application M012
RxNorm concept 1297288
Package sizes listed 1
Marketed since February 2025

Other products containing Phenylephrine

See all

Same active ingredient, different manufacturer, strength or form. Products matching on both ingredient and strength are usually interchangeable — but confirm before switching, especially with modified-release forms.

4 Way Fast Acting

Phenylephrine hydrochloride

Strength
10 mg/mL
Form
Spray
Class
alpha-1 Adrenergic Agonist
OTC

Haleon US Holdings LLC

Not stocked by us — reference only

ACTIFED

Phenylephrine hydrochloride

Strength
5 mg/1
Form
Tablet
Class
alpha-1 Adrenergic Agonist
OTC

Belmora LLC

Not stocked by us — reference only

Information only, not medical advice. Nothing on this page indicates that a medication is safe or suitable for you. Speak to a prescriber or pharmacist before starting, stopping or switching any medicine.