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Cold plus Flu Severe 325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1 tablet, coated by HYVEE INC
Cold plus Flu Severe, 325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1, tablet, coated Drug class: Expectorant; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist; alpha-1 Adrenergic Agonist. Available over the counter. Listed by HYVEE INC.
Over the counter

Cold plus Flu Severe

ACETAMINOPHEN, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, and PHENYLEPHRINE HYDROCHLORIDE

Listed by HYVEE INC

Strength
325 mg/1, 10 mg/1, 200 mg/1, 5 mg/1
Form
Tablet, Coated
Route
Oral
Class
Expectorant; Sigma-1 Agonist; Uncompetitive N…

What it contains

  • Phenylephrine Hydrochloride 325 mg/1
  • Acetaminophen 10 mg/1
  • Dextromethorphan Hydrobromide 200 mg/1
  • Guaifenesin 5 mg/1

This is a combination product. It is not interchangeable with a single-ingredient medicine containing only one of these.

FDA record

Dosage form Tablet, Coated
Route Oral
Drug class Expectorant; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist; alpha-1 Adrenergic Agonist
Approval route OTC monograph
NDC code 42507-163
FDA application M012
RxNorm concept 1110988
Package sizes listed 1
Marketed since November 2025

Other products containing Phenylephrine

See all

Same active ingredient, different manufacturer, strength or form. Products matching on both ingredient and strength are usually interchangeable — but confirm before switching, especially with modified-release forms.

4 Way Fast Acting

Phenylephrine hydrochloride

Strength
10 mg/mL
Form
Spray
Class
alpha-1 Adrenergic Agonist
OTC

Haleon US Holdings LLC

Not stocked by us — reference only

ACTIFED

Phenylephrine hydrochloride

Strength
5 mg/1
Form
Tablet
Class
alpha-1 Adrenergic Agonist
OTC

Belmora LLC

Not stocked by us — reference only

Information only, not medical advice. Nothing on this page indicates that a medication is safe or suitable for you. Speak to a prescriber or pharmacist before starting, stopping or switching any medicine.