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Medication Comparison

Compare any two to four medications side by side — what is actually in them, how strong they are, how they are taken and who makes them. Built on the 112,035 products in the US FDA National Drug Code directory.

  • 56,435Prescription
  • 55,600Over the counter
  • 3,850Active ingredients
  • 36,475We stock the ingredient

761 medications

Tick up to 4 to compare.

HISTEX-DM

DEXTROMETHORPHAN HYDROBROMIDE, PHENYLEPHRINE HYDROCHLORIDE, and TRIPR…

Strength
20 mg/5mL, 10 mg/5mL, 2.5 mg/5mL
Form
Syrup
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Allegis Pharmaceuticals, LLC

Not stocked by us — reference only

HISTEX-DM New Formulation

DEXTROMETHORPHAN HBr, PSEUDOEPHEDRINE HCI, and TRIPROLIDINE HCI

Strength
20 mg/5mL, 30 mg/5mL, 2.5 mg/5mL
Form
Syrup
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Allegis Pharmaceuticals, LLC

Not stocked by us — reference only

Histiacil Cough

DEXTROMETHORPHAN HYDROBROMIDE and GUAIFENESIN

Strength
20 mg/1, 400 mg/1
Form
Capsule
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

OPMX LLC

Not stocked by us — reference only

Honey Works Kids Honey Cough Syrup

Dextromethorphan HBr

Strength
5 mg/5mL
Form
Syrup
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

RARITAN PHARMACEUTICALS INC

Not stocked by us — reference only

Honey Works Organic Honey

Dextromethorphan HBr

Strength
20 mg/20mL
Form
Syrup
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

RARITAN PHARMACEUTICALS INC

Not stocked by us — reference only

HoneyWorks Plus Adult Nighttime Cough Syrup

dextromethorphan hbr, doxylamine succinate

Strength
20 mg/20mL, 12.5 mg/20mL
Form
Solution
Class
Antihistamine; Sigma-1 Agonist; Uncompe…
OTC

RARITAN PHARMACEUTICALS INC

Not stocked by us — reference only

Kids Multi Symptom Cold and Flu

Acetaminophen, Dextromethorphan HBr

Strength
320 mg/10mL, 5 mg/10mL
Form
Suspension
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Genexa Inc.

Not stocked by us — reference only

kirkland signature mucus dm

dextromethorphan HBr, guaifenesin

Strength
60 mg/1, 1200 mg/1
Form
Tablet, Extended Release
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC Generic

Costco Wholesale Company

Not stocked by us — reference only

Kroger Chest Congestion Relief DM

Dextromethorphan Hydrobromide / Guaifenesin

Strength
20 mg/1, 400 mg/1
Form
Tablet
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

THE KROGER CO

Not stocked by us — reference only

Kroger Maximum Strength Severe Congestion and Cough

Dextromethorphan HBr, Guaifenesin, and Phenylephrine HCl

Strength
20 mg/20mL, 400 mg/20mL, 10 mg/20mL
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

KROGER COMPANY

Not stocked by us — reference only

KROGER Mucus Relief DM Maximum Strength

Dextromethorphan HBr and Guaifenesin

Strength
20 mg/20mL, 400 mg/20mL
Form
Solution
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

KROGER COMPANY

Not stocked by us — reference only

Leader Chest Congestion Relief DM

Dextromethorphan Hydrobromide / Guaifenesin

Strength
20 mg/1, 400 mg/1
Form
Tablet
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Cardinal Health

Not stocked by us — reference only

leader childrens cough dm

dextromethorphan polistirex

Strength
30 mg/5mL
Form
Suspension
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Childrens Multi Symptom Cold

Dextromethorphan HBr, guaifenesin, Phenylephrine HCl

Strength
5 mg/5mL, 100 mg/5mL, 2.5 mg/5mL
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

CARDINAL HEALTH 110, LLC. DBA LEADER

Not stocked by us — reference only

Leader Cough DM

dextromethorphan polistirex

Strength
30 mg/5mL
Form
Suspension
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Cough DM

dextromethorphan polistirex

Strength
30 mg/5mL
Form
Suspension, Extended Release
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Leader Mucus Relief DM

dextromethorphan hydrobromide, guaifenesin

Strength
30 mg/1, 600 mg/1
Form
Tablet, Extended Release
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC Generic

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

leader tussin dm

dextromethorphan hydrobromide, guaifenesin

Strength
20 mg/20mL, 200 mg/20mL
Form
Solution
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Cardinal Health 110, LLC. dba Leader

Not stocked by us — reference only

Limpia Pecho

Dextromethorphan HBr, Guaifenesin

Strength
10 mg/5mL, 100 mg/5mL
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Llorens Pharmaceutical International Division, …

Not stocked by us — reference only

Llorens Care Tussin DM

Dextromethorphan HBr, Guaifenesin

Strength
10 mg/5mL, 100 mg/5mL
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Llorens Pharmaceutical International Division, …

Not stocked by us — reference only

LoHist DM

Brompheniramine Maleate, Dextromethorphan Hydrobromide and Phenylephr…

Strength
2 mg/5mL, 10 mg/5mL, 5 mg/5mL
Form
Liquid
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

Larken Laboratories, Inc.

Not stocked by us — reference only

Long Acting Cough Softgels

Dextromethorphan Hydrobromide

Strength
15 mg/1
Form
Capsule, Liquid Filled
Class
Sigma-1 Agonist; Uncompetitive N-methyl…
OTC

CVS PHARMACY, INC

Not stocked by us — reference only

Marcs Chest Congestion Relief DM

Dextromethorphan Hydrobromide / Guaifenesin

Strength
20 mg/1, 400 mg/1
Form
Tablet
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Marc Glassman Inc

Not stocked by us — reference only

MAX Tussin Cough and Chest Congestion DM

Dextromethorphan HBr, Guaifenesin

Strength
20 mg/10mL, 200 mg/10mL
Form
Liquid
Class
Expectorant; Sigma-1 Agonist; Uncompeti…
OTC

Akron Pharma Inc.

Not stocked by us — reference only

How to read a comparison

Same ingredient, different name

Most medications exist under several names: one brand name, one generic name, and a different brand again in another country. What matters is the active ingredient and its strength — two products with the same ingredient at the same strength are, for most purposes, the same medicine.

Strength is not a measure of quality

A 10 mg tablet is not "better" than a 5 mg one. Strength is matched to the person and the condition, and a higher one is not an upgrade. Only your prescriber can say which is right for you.

Dosage form changes more than convenience

The same ingredient as a tablet, a capsule or a liquid can be absorbed at different speeds. Modified-release forms in particular are not interchangeable with ordinary ones, even at an identical stated strength.

Approval route

NDA is an original brand-name approval. ANDA is a generic, which had to prove it delivers the ingredient to the bloodstream at a rate and extent statistically equivalent to the original. OTC monograph covers products sold without a prescription under standing FDA rules.

Controlled substances

A DEA schedule badge means the medication is federally controlled because of its potential for dependence or misuse. Schedule II is the most tightly restricted of those available by prescription. These carry extra rules on prescribing, refills and supply.

What "we supply this ingredient" means

Where we stock a product containing the same active ingredient, the card says so and links to it. That is an ingredient match — the strength, form or manufacturer of what we sell may differ from the FDA record shown, so check the product page before ordering.

This tool is for information only and is not medical advice. It cannot tell you whether a medication is safe or suitable for you, and nothing here replaces a conversation with a prescriber or pharmacist. Source data is published by the U.S. Food & Drug Administration via openFDA and is reproduced without their endorsement; the FDA states it should not be relied upon for decisions about medical care.